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4N5T

The 1.7A Crystal Structure of MDMX with a Stapled Peptide, ATSP-7041

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0043066biological_processnegative regulation of apoptotic process
A0051726biological_processregulation of cell cycle
Functional Information from PDB Data
site_idAC1
Number of Residues12
DetailsBINDING SITE FOR RESIDUE 2JH B 26
ChainResidue
AMET50
BSER28
BALA29
BALA30
AVAL89
ALEU95
ATYR96
BTYR22
BTRP23
BALA24
BGLN25
BMK827

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues83
DetailsDomain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

238895

PDB entries from 2025-07-16

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