4N49
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Protein in complex with m7GpppG and SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 | polymer | 428 | 48935.8 | 1 | UniProt (Q8N1G2) Pfam (PF01728) | Homo sapiens (human) | Cap1 2'O-ribose methyltransferase 1, MTr1, hMTr1, FtsJ methyltransferase domain-containing protein 2, Interferon-stimulated gene 95 kDa protein, ISG95 |
| 2 | B (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (145712080) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (5136) PubChem (34755) PubChem (9865603) PubChem (12312798) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 3 | C (A) | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (MGT) | |||
| 4 | D (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 5 | E (A) | water | water | 18.0 | 542 | Chemie (HOH) |
Sequence modifications
A: 126 - 550 (UniProt: Q8N1G2)
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | - | expression tag |
| Ala 124 | - | expression tag |
| Met 125 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48935.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 960.6 | |
| All* | Total formula weight | 49896.4 |
