4N49
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Protein in complex with m7GpppG and SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 | polymer | 428 | 48935.8 | 1 | UniProt (Q8N1G2) Pfam (PF01728) In PDB | Homo sapiens (human) | Cap1 2'O-ribose methyltransferase 1, MTr1, hMTr1, FtsJ methyltransferase domain-containing protein 2, Interferon-stimulated gene 95 kDa protein, ISG95 |
| 2 | A | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 3 | A | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (MGT) | |||
| 4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 542 | Chemie (HOH) |
Sequence modifications
A: 126 - 550 (UniProt: Q8N1G2)
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | - | expression tag |
| Ala 124 | - | expression tag |
| Met 125 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 48935.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 960.6 | |
| All* | Total formula weight | 49896.4 |
