4N48
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Protein in complex with capped RNA fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 | polymer | 428 | 48935.8 | 2 | UniProt (Q8N1G2) Pfam (PF01728) | Homo sapiens (human) | Cap1 2'O-ribose methyltransferase 1, MTr1, hMTr1, FtsJ methyltransferase domain-containing protein 2, Interferon-stimulated gene 95 kDa protein, ISG95 |
| 2 | C, D (D, G) | capped RNA | polymer | 4 | 1240.8 | 2 | |||
| 3 | E, F (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (9865603) PubChem (145712080) PubChem (12312798) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 4 | G, H (D, G) | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE | non-polymer | 539.2 | 2 | Chemie (MGT) | |||
| 5 | I, J, K, L (A, B, D, G) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A, B: 126 - 550 (UniProt: Q8N1G2)
| PDB | External Database | Details |
|---|---|---|
| Gly 123 | - | expression tag |
| Ala 124 | - | expression tag |
| Met 125 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 100353.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1875.3 | |
| All* | Total formula weight | 102228.4 |
