4N48
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 Protein in complex with capped RNA fragment
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAM A 601 |
| Chain | Residue |
| A | ASN234 |
| A | LEU302 |
| A | ASN306 |
| A | GLY334 |
| A | ASP335 |
| A | ILE336 |
| A | THR337 |
| A | ASP364 |
| A | GLY365 |
| A | GLY366 |
| A | HOH715 |
| A | ALA236 |
| A | HOH724 |
| D | G1 |
| D | A2 |
| A | CYS277 |
| A | ALA278 |
| A | GLY279 |
| A | PRO280 |
| A | GLY281 |
| A | GLY282 |
| A | PHE283 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SAM B 601 |
| Chain | Residue |
| B | ASN234 |
| B | ALA236 |
| B | CYS277 |
| B | ALA278 |
| B | GLY279 |
| B | PRO280 |
| B | GLY281 |
| B | GLY282 |
| B | PHE283 |
| B | THR301 |
| B | LEU302 |
| B | ASN306 |
| B | GLY334 |
| B | ASP335 |
| B | ILE336 |
| B | THR337 |
| B | ASP364 |
| B | GLY365 |
| B | GLY366 |
| B | HOH722 |
| B | HOH723 |
| G | G1 |
| G | A2 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE MGT D 101 |
| Chain | Residue |
| A | LYS203 |
| A | SER204 |
| A | PHE206 |
| A | ASP207 |
| A | MET214 |
| A | ARG218 |
| A | GLU373 |
| A | ASN374 |
| A | GLN376 |
| A | ALA438 |
| A | ASN439 |
| A | SER440 |
| A | HOH741 |
| A | HOH750 |
| D | G1 |
| D | HOH201 |
| D | HOH203 |
| D | HOH206 |
| D | HOH207 |
| D | HOH208 |
| D | HOH210 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE MGT G 101 |
| Chain | Residue |
| B | LYS203 |
| B | SER204 |
| B | PHE206 |
| B | ASP207 |
| B | MET214 |
| B | ARG218 |
| B | GLU373 |
| B | ASN374 |
| B | GLN376 |
| B | ALA438 |
| B | ASN439 |
| G | G1 |
| G | HOH201 |
| G | HOH202 |
| G | HOH205 |
| G | HOH206 |
| G | HOH207 |
| G | HOH209 |
| G | HOH213 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"21310715","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"21310715","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24402442","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N48","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N49","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
