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4MZF

Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2a) peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Peptide from Histone H3.2polymer91132.41UniProt (Q71DI3)Homo sapiensHistone H3/m, Histone H3/o
2B
(B)
Spindlin-1polymer22425609.81UniProt (Q9Y657)
Pfam (PF02513)
Homo sapiens (human)Sp1, Ovarian cancer-related protein
3C, D
(B)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4E
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5F, G
(A, B)
waterwater18.0113Chemie (HOH)
Sequence modifications
B: 50 - 262 (UniProt: Q9Y657)
PDBExternal DatabaseDetails
Gly 39-expression tag
Ser 40-expression tag
Ser 41-expression tag
His 42-expression tag
His 43-expression tag
His 44-expression tag
His 45-expression tag
His 46-expression tag
His 47-expression tag
Gly 48-expression tag
Ser 49-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight26742.1
Non-Polymers*Number of molecules3
Total formula weight95.2
All*Total formula weight26837.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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