4MZ1
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Inosine-5'-monophosphate dehydrogenase | polymer | 385 | 41053.2 | 3 | UniProt (Q0P9J4) Pfam (PF00478) | Campylobacter jejuni subsp. jejuni | IMP dehydrogenase, IMPD, IMPDH |
| 2 | D, K, S (A, B, C) | INOSINIC ACID | non-polymer | 348.2 | 3 | Chemie (IMP) | |||
| 3 | E, L, T (A, B, C) | 1-(4-bromophenyl)-3-{2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}urea | non-polymer | 373.3 | 3 | Chemie (2F1) | |||
| 4 | F, M, U (A, B, C) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 5 | G, O, P, V (A, B, C) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | H, I, J, N, Q... (A, B, C) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 7 | R, X (C) | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 8 | AA, Y, Z (C, A, B) | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 91 (UniProt: Q0P9J4)
A, B, C: 196 - 485 (UniProt: Q0P9J4)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 92 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 123159.5 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 3356.0 | |
| All* | Total formula weight | 126515.5 |
