4MZ1
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Inosine-5'-monophosphate dehydrogenase | polymer | 385 | 41053.2 | 3 | UniProt (Q0P9J4) Pfam (PF00478) In PDB | Campylobacter jejuni subsp. jejuni | IMP dehydrogenase, IMPD, IMPDH |
2 | A, B, C | INOSINIC ACID | non-polymer | 348.2 | 3 | Chemie (IMP) | |||
3 | A, B, C | 1-(4-bromophenyl)-3-{2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}urea | non-polymer | 373.3 | 3 | Chemie (2F1) | |||
4 | A, B, C | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
5 | A, B, C | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
6 | A, B, C | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
7 | C | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
8 | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 91 (UniProt: Q0P9J4)
A, B, C: 196 - 485 (UniProt: Q0P9J4)
PDB | External Database | Details |
---|---|---|
Ser -2 | - | expression tag |
Asn -1 | - | expression tag |
Ala 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 92 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 123159.5 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 3356.0 | |
All* | Total formula weight | 126515.5 |