Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003938 | molecular_function | IMP dehydrogenase activity |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0003938 | molecular_function | IMP dehydrogenase activity |
| C | 0006164 | biological_process | purine nucleotide biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE IMP A 500 |
| Chain | Residue |
| A | ALA46 |
| A | MET355 |
| A | GLY357 |
| A | SER358 |
| A | TYR381 |
| A | GLY383 |
| A | MET384 |
| A | GLY385 |
| A | GLU411 |
| A | GLY412 |
| A | 2F1501 |
| A | MET48 |
| A | HOH601 |
| A | HOH606 |
| A | HOH610 |
| A | HOH615 |
| A | HOH628 |
| A | GLY298 |
| A | SER299 |
| A | ILE300 |
| A | CYS301 |
| A | ASP334 |
| A | GLY335 |
| A | GLY336 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2F1 A 501 |
| Chain | Residue |
| A | VAL22 |
| A | ALA246 |
| A | THR303 |
| A | GLY385 |
| A | GLU411 |
| A | GLY439 |
| A | TYR440 |
| A | IMP500 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 502 |
| Chain | Residue |
| A | GLY296 |
| A | GLY298 |
| A | CYS301 |
| A | GLU465 |
| A | SER466 |
| A | HIS467 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PO4 A 504 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 505 |
| Chain | Residue |
| A | TYR378 |
| A | ARG416 |
| A | THR472 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 A 506 |
| Chain | Residue |
| A | TYR373 |
| A | TYR373 |
| A | GLN374 |
| A | GLN374 |
| site_id | AC8 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE IMP B 500 |
| Chain | Residue |
| B | ALA46 |
| B | MET48 |
| B | ASN273 |
| B | GLY298 |
| B | SER299 |
| B | ILE300 |
| B | CYS301 |
| B | ASP334 |
| B | GLY335 |
| B | GLY336 |
| B | MET355 |
| B | GLY357 |
| B | SER358 |
| B | TYR381 |
| B | GLY383 |
| B | MET384 |
| B | GLY385 |
| B | GLU411 |
| B | GLY412 |
| B | 2F1501 |
| B | HOH604 |
| B | HOH636 |
| B | HOH637 |
| B | HOH654 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 2F1 B 501 |
| Chain | Residue |
| B | ALA246 |
| B | THR303 |
| B | MET384 |
| B | GLY385 |
| B | MET390 |
| B | GLU411 |
| B | GLY439 |
| B | TYR440 |
| B | IMP500 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 502 |
| Chain | Residue |
| B | GLY296 |
| B | GLY298 |
| B | CYS301 |
| B | GLU465 |
| B | SER466 |
| B | HIS467 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 503 |
| Chain | Residue |
| B | TYR378 |
| B | ARG416 |
| B | THR472 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 504 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 505 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PO4 B 506 |
| Chain | Residue |
| B | GLN226 |
| B | ARG229 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY C 501 |
| Chain | Residue |
| B | TYR373 |
| B | GLN374 |
| C | TYR373 |
| site_id | BC7 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE IMP C 502 |
| Chain | Residue |
| C | GLY298 |
| C | SER299 |
| C | ILE300 |
| C | CYS301 |
| C | ASP334 |
| C | GLY335 |
| C | GLY336 |
| C | MET355 |
| C | GLY357 |
| C | SER358 |
| C | TYR381 |
| C | GLY383 |
| C | MET384 |
| C | GLY385 |
| C | GLU411 |
| C | GLY412 |
| C | 2F1503 |
| C | HOH615 |
| C | HOH625 |
| C | HOH655 |
| C | HOH656 |
| C | ALA46 |
| C | MET48 |
| site_id | BC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 2F1 C 503 |
| Chain | Residue |
| C | ALA246 |
| C | HIS247 |
| C | THR303 |
| C | MET384 |
| C | GLY385 |
| C | MET390 |
| C | GLU411 |
| C | GLY439 |
| C | TYR440 |
| C | IMP502 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K C 504 |
| Chain | Residue |
| C | GLY296 |
| C | GLY298 |
| C | CYS301 |
| C | GLU465 |
| C | SER466 |
| C | HIS467 |
| site_id | CC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C 505 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 C 506 |
| Chain | Residue |
| C | ARG376 |
| C | TYR378 |
| C | ARG416 |
| C | THR472 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY C 507 |
| Chain | Residue |
| C | ILE75 |
| C | GLN226 |
| C | MET227 |
| C | ASP228 |
| C | ARG229 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGIGpGSICtT |
| Chain | Residue | Details |
| A | VAL291-THR303 | |
4MZ1
