4MLR

dihydrodipicolinate synthase from C. jejuni, Y110F mutation with pyruvate and Lysine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	dihydrodipicolinate synthase	polymer	306	33750.8	8	UniProt (Q9PPB4) Pfam (PF00701)	campylobacter jejuni	HTPA synthase, 4-hydroxy-tetrahydrodipicolinate synthase
2	AA, DA, HA, I, J... (F, G, H, A, B...)	LYSINE	non-polymer		147.2	8	Chemie (LYS)
3	EA, FA, GA, K, M... (G, A, D, E)	1,2-ETHANEDIOL	non-polymer		62.1	9	Chemie (EDO)
4	CA, L (F, A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
5	P, S (B, C)	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
6	BA, IA, Q, T, X (F, H, B, C, E)	TRIETHYLENE GLYCOL	non-polymer		150.2	5	Chemie (PGE)
7	U (C)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	JA, KA, LA, MA, NA... (A, B, C, D, E...)	water	water		18.0	202	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 298 (UniProt: Q9PPB4)

PDB	External Database	Details
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag
Phe 110	Tyr 110	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	270006.2
Non-Polymers*	Number of molecules	27
	Total formula weight	3085.7
All*	Total formula weight	273091.8

*Water molecules are not included.