4MHG
Crystal structure of ETV6 bound to a specific DNA sequence
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B | Specific 14 bp DNA | polymer | 14 | 4338.8 | 1 | synthetic construct | ||
| 2 | C | Complementary Specific 14 bp DNA | polymer | 14 | 4222.7 | 1 | synthetic construct | ||
| 3 | A | Transcription factor ETV6 | polymer | 102 | 12450.4 | 1 | UniProt (P97360) Pfam (PF00178) In PDB | Mus musculus (mouse) | ETS translocation variant 6, ETS-related protein Tel1, Tel |
| 4 | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A: 329 - 426 (UniProt: P97360)
| PDB | External Database | Details |
|---|---|---|
| Gly 325 | - | expression tag |
| Ser 326 | - | expression tag |
| His 327 | - | expression tag |
| Met 328 | - | expression tag |
| Ser 334 | Cys 334 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 21011.9 | |
| All* | Total formula weight | 21011.9 |
