4MHG

Crystal structure of ETV6 bound to a specific DNA sequence

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PROSITE/UniProt

site_id	PS00346
Number of Residues	16
Details	ETS_DOMAIN_2 Ets-domain signature 2. RtnMtYEkMSRALRhY

Chain	Residue	Details
A	ARG382-TYR397

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	81
Details	DNA_BIND: ETS => ECO:0000255|PROSITE-ProRule:PRU00237

Chain	Residue	Details
A	ARG335-MET416

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site_id	SWS_FT_FI2
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:P41212

Chain	Residue	Details
A	LYS399
A	LYS417

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