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4MBB

Cubic crystal form of PIR1 dual specificity phosphatase core

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RNA/RNP complex-1-interacting phosphatasepolymer18421477.51UniProt (O75319)
Pfam (PF00782)
Homo sapiens (human)Dual specificity protein phosphatase 11, Phosphatase that interacts with RNA/RNP complex 1
2B
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
3C
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
4D
(A)
waterwater18.0181Chemie (HOH)
Sequence modifications
A: 29 - 207 (UniProt: O75319)
PDBExternal DatabaseDetails
Gly 24-expression tag
Pro 25-expression tag
Leu 26-expression tag
Gly 27-expression tag
Ser 28-expression tag
Ser 152Cys 152engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight21477.5
Non-Polymers*Number of molecules2
Total formula weight130.4
All*Total formula weight21607.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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