4MBB
Cubic crystal form of PIR1 dual specificity phosphatase core
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 301 |
| Chain | Residue |
| A | THR94 |
| A | TYR95 |
| A | THR96 |
| A | THR153 |
| A | ARG158 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 302 |
| Chain | Residue |
| A | LEU156 |
| A | ASN157 |
| A | ARG158 |
| A | HOH414 |
| A | SER152 |
| A | THR153 |
| A | HIS154 |
| A | GLY155 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160, ECO:0000269|PubMed:24447265, ECO:0000305|PubMed:9685386 |
| Chain | Residue | Details |
| A | SER152 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255 |
| Chain | Residue | Details |
| A | ARG158 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:24531476 |
| Chain | Residue | Details |
| A | THR153 |
