4MBB
Cubic crystal form of PIR1 dual specificity phosphatase core
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 301 |
| Chain | Residue |
| A | THR94 |
| A | TYR95 |
| A | THR96 |
| A | THR153 |
| A | ARG158 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 302 |
| Chain | Residue |
| A | LEU156 |
| A | ASN157 |
| A | ARG158 |
| A | HOH414 |
| A | SER152 |
| A | THR153 |
| A | HIS154 |
| A | GLY155 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24447265","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9685386","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24531476","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
