4M8O
TERNARY COMPLEX OF DNA POLYMERASE EPSILON WITH AN INCOMING dATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase epsilon catalytic subunit A | polymer | 1228 | 141477.6 | 1 | UniProt (P21951) Pfam (PF03104) Pfam (PF22634) | Saccharomyces cerevisiae (Baker's yeast) | DNA polymerase II subunit A |
| 2 | B (P) | PRIMER DNA | polymer | 11 | 4006.5 | 1 | |||
| 3 | C (T) | TEMPLATE DNA | polymer | 16 | 5840.2 | 1 | |||
| 4 | D (A) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 1 | Chemie (DTP) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | G, H (A) | 2-AMINOETHANESULFONIC ACID | non-polymer | 125.1 | 2 | Chemie (TAU) | |||
| 8 | I, J (P) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 9 | K, L, M (A, P, T) | water | water | 18.0 | 459 | Chemie (HOH) |
Sequence modifications
A: 1 - 1228 (UniProt: P21951)
| PDB | External Database | Details |
|---|---|---|
| Ala 290 | Asp 290 | engineered mutation |
| Ala 292 | Glu 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 151324.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 902.1 | |
| All* | Total formula weight | 152226.4 |
