4M8O

TERNARY COMPLEX OF DNA POLYMERASE EPSILON WITH AN INCOMING dATP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006260	biological_process	DNA replication
A	0006281	biological_process	DNA repair
A	0008622	cellular_component	epsilon DNA polymerase complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE DTP A 1301

Chain	Residue
A	ASP640
A	ASN828
A	ASP877
A	MG1302
A	HOH1430
A	HOH1432
A	HOH1655
A	HOH1742
P	DOC11
T	DT5
T	DG6
A	VAL641
A	ALA642
A	SER643
A	MET644
A	TYR645
A	ARG781
A	LYS785
A	LYS824

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 1302

Chain	Residue
A	ASP640
A	VAL641
A	ASP877
A	DTP1301

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1303

Chain	Residue
A	CYS665
A	CYS668
A	CYS677
A	CYS763

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE TAU A 1304

Chain	Residue
A	LYS427
A	ARG428
A	HOH1741
A	HOH1799

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE TAU A 1305

Chain	Residue
A	ALA979
A	GLU980
A	LEU981
A	LYS982
A	LYS987
A	HOH1754

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL P 101

Chain	Residue
P	5IU10
P	HOH204

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL P 102

Chain	Residue
P	5IU9

---