4M62
Ontogeny of recognition specificity and functionality for the anti-HIV neutralizing antibody 4E10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (L, M) | GEP2 FV light chain | polymer | 113 | 12211.6 | 2 | UniProt (P18136) Pfam (PF07686) UniProt (by SIFTS) (P01619) | Homo sapiens (human) | Ig kappa chain V-III region HIC |
| 2 | B, D (H, I) | GEP2 FV heavy chain | polymer | 127 | 13413.0 | 2 | Homo sapiens (human) | ||
| 3 | E, F (S, T) | T117 | polymer | 155 | 17618.0 | 2 | synthetic construct (artificial gene) | ||
| 4 | G, H, I, J, K... (L, M, S, T) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 5 | P, Q, R, S, T... (L, H, M, I, S...) | water | water | 18.0 | 696 | Chemie (HOH) |
Sequence modifications
L, M: 1 - 108 (UniProt: P18136)
| PDB | External Database | Details |
|---|---|---|
| Ser 96 | Trp 117 | conflict |
| Leu 109 | - | expression tag |
| Val 110 | - | expression tag |
| Pro 111 | - | expression tag |
| Arg 112 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 86485.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 864.6 | |
| All* | Total formula weight | 87349.8 |
