4M62
Ontogeny of recognition specificity and functionality for the anti-HIV neutralizing antibody 4E10
Functional Information from GO Data
Chain | GOid | namespace | contents |
L | 0002250 | biological_process | adaptive immune response |
L | 0003094 | biological_process | glomerular filtration |
L | 0003823 | molecular_function | antigen binding |
L | 0005576 | cellular_component | extracellular region |
L | 0005615 | cellular_component | extracellular space |
L | 0005886 | cellular_component | plasma membrane |
L | 0006955 | biological_process | immune response |
L | 0019731 | biological_process | antibacterial humoral response |
L | 0019814 | cellular_component | immunoglobulin complex |
L | 0070062 | cellular_component | extracellular exosome |
L | 0071748 | cellular_component | monomeric IgA immunoglobulin complex |
L | 0071751 | cellular_component | secretory IgA immunoglobulin complex |
L | 0071756 | cellular_component | pentameric IgM immunoglobulin complex |
L | 0072562 | cellular_component | blood microparticle |
M | 0002250 | biological_process | adaptive immune response |
M | 0003094 | biological_process | glomerular filtration |
M | 0003823 | molecular_function | antigen binding |
M | 0005576 | cellular_component | extracellular region |
M | 0005615 | cellular_component | extracellular space |
M | 0005886 | cellular_component | plasma membrane |
M | 0006955 | biological_process | immune response |
M | 0019731 | biological_process | antibacterial humoral response |
M | 0019814 | cellular_component | immunoglobulin complex |
M | 0070062 | cellular_component | extracellular exosome |
M | 0071748 | cellular_component | monomeric IgA immunoglobulin complex |
M | 0071751 | cellular_component | secretory IgA immunoglobulin complex |
M | 0071756 | cellular_component | pentameric IgM immunoglobulin complex |
M | 0072562 | cellular_component | blood microparticle |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 L 201 |
Chain | Residue |
L | PRO59 |
L | ASP60 |
L | ARG61 |
L | HOH391 |
L | HOH392 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 L 202 |
Chain | Residue |
L | HOH316 |
L | HOH397 |
L | ARG45 |
L | PRO59 |
L | ARG61 |
L | HOH314 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 M 201 |
Chain | Residue |
M | ARG45 |
M | PRO59 |
M | ARG61 |
M | PHE62 |
M | HOH302 |
M | HOH337 |
M | HOH387 |
site_id | AC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 S 201 |
Chain | Residue |
I | THR28 |
I | PHE29 |
I | SER30 |
I | HOH281 |
S | ARG15 |
S | ARG16 |
S | HIS17 |
S | HOH311 |
site_id | AC5 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 S 202 |
Chain | Residue |
L | LYS107 |
L | ARG108 |
L | LEU109 |
L | VAL110 |
S | ARG20 |
S | SER37 |
S | HOH337 |
S | HOH352 |
S | HOH397 |
site_id | AC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 T 201 |
Chain | Residue |
H | THR28 |
H | PHE29 |
H | SER30 |
H | HOH300 |
T | ARG15 |
T | ARG16 |
T | HIS17 |
site_id | AC7 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE SO4 T 202 |
Chain | Residue |
H | HOH214 |
M | ARG108 |
M | ARG112 |
T | HIS17 |
T | PRO38 |
T | HOH303 |
T | HOH304 |
T | HOH322 |
T | HOH342 |
T | HOH390 |
site_id | AC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 T 203 |
Chain | Residue |
S | ASN29 |
S | LYS33 |
S | HOH399 |
T | LYS33 |
T | HOH336 |
T | HOH338 |
T | HOH412 |
T | HOH419 |
site_id | AC9 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE SO4 T 204 |
Chain | Residue |
T | ARG82 |