4LV8

Murine IRGa6 bound to Toxoplasma ROP5C, a pseudokinase GDI

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Rhoptry protein 5 C	polymer	371	41347.3	1	UniProt (I6ZQR7)	Toxoplasma gondii type I
2	B (B)	Interferon-inducible GTPase 1	polymer	423	48484.5	1	UniProt (Q9QZ85) Pfam (PF05049)	Mus musculus (mouse)
3	C (A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
4	D (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
5	E, F, G, H, I... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	10	Chemie (EDO)
6	L (B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
7	P, Q (A, B)	water	water		18.0	515	Chemie (HOH)

Sequence modifications

A: 175 - 541 (UniProt: I6ZQR7)

PDB	External Database	Details
Gly 171	-	expression tag
Ser 172	-	expression tag
His 173	-	expression tag
Met 174	-	expression tag

B: 1 - 413 (UniProt: Q9QZ85)

PDB	External Database	Details
Gly -9	-	expression tag
Ser -8	-	expression tag
Pro -7	-	expression tag
Gly -6	-	expression tag
Ile -5	-	expression tag
Pro -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Thr -1	-	expression tag
Thr 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	89831.8
Non-Polymers*	Number of molecules	13
	Total formula weight	1515.4
All*	Total formula weight	91347.2

*Water molecules are not included.