4LTC
Crystal structure of yeast 20S proteasome in complex with enone carmaphycin analogue 6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, H (A, O) | Proteasome subunit alpha type-2 | polymer | 250 | 27191.8 | 2 | UniProt (P23639) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit Y7, Multicatalytic endopeptidase complex subunit Y7, Proteasome component Y7, Proteinase YSCE subunit 7 |
| 2 | B, I (B, P) | Proteasome subunit alpha type-3 | polymer | 258 | 28748.2 | 2 | UniProt (P23638) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit Y13, Multicatalytic endopeptidase complex subunit Y13, Proteasome component Y13, Proteinase YSCE subunit 13 |
| 3 | C, J (C, Q) | Proteasome subunit alpha type-4 | polymer | 254 | 28478.1 | 2 | UniProt (P40303) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit PRE6, Multicatalytic endopeptidase complex subunit PRE6, Proteasome component PRE6, Proteinase YSCE subunit PRE6 |
| 4 | D, K (D, R) | Proteasome subunit alpha type-5 | polymer | 260 | 28649.1 | 2 | UniProt (P32379) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit PUP2, Multicatalytic endopeptidase complex subunit PUP2, Proteasome component PUP2, Proteinase YSCE subunit PUP2 |
| 5 | E, L (E, S) | Proteasome subunit alpha type-6 | polymer | 234 | 25634.0 | 2 | UniProt (P40302) Pfam (PF00227) Pfam (PF10584) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit PRE5, Multicatalytic endopeptidase complex subunit PRE5, Proteasome component PRE5, Proteinase YSCE subunit PRE5 |
| 6 | F, M (F, T) | Probable proteasome subunit alpha type-7 | polymer | 287 | 31443.9 | 2 | UniProt (P21242) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit C1, Multicatalytic endopeptidase complex subunit C1, Proteasome component C1, Proteinase YSCE subunit 1 |
| 7 | G, N (G, U) | Proteasome subunit alpha type-1 | polymer | 252 | 28033.8 | 2 | UniProt (P21243) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit C7-alpha, Multicatalytic endopeptidase complex C7, Proteasome component C7-alpha, Proteasome component Y8, Proteinase YSCE subunit 7, SCL1 suppressor protein |
| 8 | O, V (H, V) | Proteasome subunit beta type-2 | polymer | 232 | 25114.5 | 2 | UniProt (P25043) Pfam (PF00227) Pfam (PF12465) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit PUP1, Multicatalytic endopeptidase complex subunit PUP1, Proteasome component PUP1, Proteinase YSCE subunit PUP1 |
| 9 | P, W (I, W) | Proteasome subunit beta type-3 | polymer | 205 | 22627.8 | 2 | UniProt (P25451) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit PUP3, Multicatalytic endopeptidase complex subunit PUP3, Proteasome component PUP3 |
| 10 | Q, X (J, X) | Proteasome subunit beta type-4 | polymer | 198 | 22545.7 | 2 | UniProt (P22141) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit C11, Multicatalytic endopeptidase complex subunit C11, Proteasome component C11, Proteinase YSCE subunit 11 |
| 11 | R, Y (K, Y) | Proteasome subunit beta type-5 | polymer | 212 | 23325.2 | 2 | UniProt (P30656) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit PRE2, Multicatalytic endopeptidase complex subunit PRE2, Proteasome component PRE2, Proteinase YSCE subunit PRE2 |
| 12 | S, Z (L, Z) | Proteasome subunit beta type-6 | polymer | 222 | 24883.9 | 2 | UniProt (P23724) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Multicatalytic endopeptidase complex subunit C5, Proteasome component C5 |
| 13 | AA, T (M, a) | Proteasome subunit beta type-7 | polymer | 233 | 25945.5 | 2 | UniProt (P30657) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit PRE4, Multicatalytic endopeptidase complex subunit PRE4, Proteasome component PRE4, Proteinase YSCE subunit PRE4 |
| 14 | BA, U (N, b) | Proteasome subunit beta type-1 | polymer | 196 | 21517.2 | 2 | UniProt (P38624) Pfam (PF00227) | Saccharomyces cerevisiae (Baker's yeast) | Macropain subunit PRE3, Multicatalytic endopeptidase complex subunit PRE3, Proteasome component PRE3, Proteinase YSCE subunit PRE3 |
| 15 | CA, DA (K, Y) | N-hexanoyl-L-valyl-N~1~-[(4S,5S,6R)-5-hydroxy-2,6-dimethyloctan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide | non-polymer | 526.8 | 2 | BIRD (PRD_001161) Chemie (EC6) | |||
| 16 | AB, BB, CB, DB, EA... (W, X, Y, Z, A...) | water | water | 18.0 | 2607 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 28 |
| Total formula weight | 728277.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1053.5 | |
| All* | Total formula weight | 729331.1 |
