4LT5

Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Naegleria Tet-like dioxygenase	polymer	327	37374.1	1	UniProt (D2W6T1)	Naegleria gruberi (Amoeba)
2	B (B)	DNA	polymer	14	4293.8	1
3	C (C)	DNA	polymer	14	4293.8	1
4	D (A)	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
5	E, F, G, H, I... (A, C)	1,2-ETHANEDIOL	non-polymer		62.1	9	Chemie (EDO)
6	L, M, N, O (A)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
7	P (A)	N-OXALYLGLYCINE	non-polymer		147.1	1	Chemie (OGA)
8	S, T, U, V (A, B, C)	water	water		18.0	100	Chemie (HOH)

Sequence modifications

A: 2 - 321 (UniProt: D2W6T1)

PDB	External Database	Details
Met -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	45961.8
Non-Polymers*	Number of molecules	15
	Total formula weight	1144.9
All*	Total formula weight	47106.7

*Water molecules are not included.