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4LKM

Crystal structure of Plk1 Polo-box domain in complex with PL-74

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Serine/threonine-protein kinase PLK1polymer23126729.52UniProt (P53350)
Pfam (PF00659)
Homo sapiens (human)Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13
2B, D
(B, D)
PL-74polymer91037.22synthetic construct
3E, G
(A, C)
SULFATE IONnon-polymer96.12Chemie (SO4)
4F, H
(B, D)
GLYCEROLnon-polymer92.12Chemie (GOL)
5I, J, K, L
(A, B, C, D)
waterwater18.0202Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight55533.4
Non-Polymers*Number of molecules4
Total formula weight376.3
All*Total formula weight55909.7
*Water molecules are not included.

237423

PDB entries from 2025-06-11

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