4LK3
Crystal structure of Human UDP-xylose synthase R236A substitution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | UDP-glucuronic acid decarboxylase 1 | polymer | 336 | 37838.1 | 6 | UniProt (Q8NBZ7) Pfam (PF16363) | Homo sapiens (human) | UDP-glucuronate decarboxylase 1, UGD, UXS-1 |
| 2 | DA, G, L, Q, U... (F, A, B, C, D...) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 6 | Chemie (NAD) | |||
| 3 | H, M, V (A, B, D) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 3 | Chemie (UDP) | |||
| 4 | BA, EA, I, N, R... (E, F, A, B, C...) | URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID | non-polymer | 580.3 | 6 | Chemie (UGA) | |||
| 5 | CA, GA, J, K, O... (E, F, A, B, C...) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 6 | AA, FA, S (E, F, C) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 3 | Chemie (POP) | |||
| 7 | HA, IA, JA, KA (B, C, D, E) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 85 - 420 (UniProt: Q8NBZ7)
| PDB | External Database | Details |
|---|---|---|
| Ala 236 | Arg 236 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 227028.4 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 10067.2 | |
| All* | Total formula weight | 237095.5 |
