4LG8
Crystal structure of PRPF19 WD40 repeats
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Pre-mRNA-processing factor 19 | polymer | 354 | 39059.9 | 1 | UniProt (Q9UMS4) Pfam (PF00400) In PDB | Homo sapiens (human) | Nuclear matrix protein 200, PRP19/PSO4 homolog, hPso4, Senescence evasion factor |
2 | A | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
3 | A | UNKNOWN ATOM OR ION | non-polymer | 14 | Chemie (UNX) | ||||
4 | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A: 169 - 504 (UniProt: Q9UMS4)
PDB | External Database | Details |
---|---|---|
Met 151 | - | expression tag |
His 152 | - | expression tag |
His 153 | - | expression tag |
His 154 | - | expression tag |
His 155 | - | expression tag |
His 156 | - | expression tag |
His 157 | - | expression tag |
Ser 158 | - | expression tag |
Ser 159 | - | expression tag |
Gly 160 | - | expression tag |
Arg 161 | - | expression tag |
Glu 162 | - | expression tag |
Asn 163 | - | expression tag |
Leu 164 | - | expression tag |
Tyr 165 | - | expression tag |
Phe 166 | - | expression tag |
Gln 167 | - | expression tag |
Gly 168 | - | expression tag |
Glu 189 | Lys 189 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39059.9 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 46.0 | |
All* | Total formula weight | 39105.9 |