4LEZ
Structure of mouse cGAS bound to an 18bp DNA and cGAS product
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Cyclic GMP-AMP synthase | polymer | 366 | 42984.7 | 2 | UniProt (Q8C6L5) Pfam (PF03281) Pfam (PF20266) In PDB | Mus musculus (mouse) | cGAMP synthase, cGAS, m-cGAS, Mab-21 domain-containing protein 1 |
2 | E, F, I, J | 18bp dsDNA | polymer | 18 | 5514.6 | 4 | |||
3 | A, C | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | A, C | cGAMP | non-polymer | 674.4 | 2 | Chemie (1SY) | |||
5 | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 108027.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1479.6 | |
All* | Total formula weight | 109507.4 |