4LEZ
Structure of mouse cGAS bound to an 18bp DNA and cGAS product
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Cyclic GMP-AMP synthase | polymer | 366 | 42984.7 | 2 | UniProt (Q8C6L5) Pfam (PF03281) Pfam (PF20266) | Mus musculus (mouse) | cGAMP synthase, cGAS, m-cGAS, Mab-21 domain-containing protein 1 |
| 2 | C, D, E, F (E, F, I, J) | 18bp dsDNA | polymer | 18 | 5514.6 | 4 | |||
| 3 | G, I (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | H, J (A, C) | cGAMP | non-polymer | 674.4 | 2 | Chemie (1SY) | |||
| 5 | K, L, M, N, O... (A, C, E, F, I...) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 108027.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1479.6 | |
| All* | Total formula weight | 109507.4 |
