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4LEZ

Structure of mouse cGAS bound to an 18bp DNA and cGAS product

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CCyclic GMP-AMP synthasepolymer36642984.72UniProt (Q8C6L5)
Pfam (PF03281)
Pfam (PF20266)
In PDB
Mus musculus (mouse)cGAMP synthase, cGAS, m-cGAS, Mab-21 domain-containing protein 1
2E, F, I, J18bp dsDNApolymer185514.64
3A, CZINC IONnon-polymer65.42Chemie (ZN)
4A, CcGAMPnon-polymer674.42Chemie (1SY)
5waterwater18.0151Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight108027.7
Non-Polymers*Number of molecules4
Total formula weight1479.6
All*Total formula weight109507.4
*Water molecules are not included.

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PDB entries from 2024-07-17

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