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4L9M

Autoinhibited state of the Ras-specific exchange factor RasGRP1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARAS guanyl-releasing protein 1polymer55964212.61UniProt (O95267)
Pfam (PF00618)
Pfam (PF00617)
Pfam (PF00130)
In PDB
Homo sapiens (human)Calcium and DAG-regulated guanine nucleotide exchange factor II, CalDAG-GEFII, Ras guanyl-releasing protein
2ACITRIC ACIDnon-polymer192.11Chemie (CIT)
3AGLYCEROLnon-polymer92.11Chemie (GOL)
4AZINC IONnon-polymer65.42Chemie (ZN)
5waterwater18.06Chemie (HOH)
Sequence modifications
A: 50 - 607 (UniProt: O95267)
PDBExternal DatabaseDetails
Ser 49-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight64212.6
Non-Polymers*Number of molecules4
Total formula weight415.0
All*Total formula weight64627.6
*Water molecules are not included.

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PDB entries from 2024-04-24

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