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4L4I

Crystal structure of mouse Ryanodine Receptor isoform 2 (RyR2) 1-547 disease mutant R420Q

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARyanodine receptor 2polymer54761549.61UniProt (E9Q401)
Pfam (PF08709)
Pfam (PF02815)
Pfam (PF01365)
In PDB
Mus musculus (mouse)RYR-2, RyR2, Cardiac muscle ryanodine receptor, Cardiac muscle ryanodine receptor-calcium release channel, Type 2 ryanodine receptor, Cardiac Ca2+ release channel
2AGLYCEROLnon-polymer92.11Chemie (GOL)
3waterwater18.064Chemie (HOH)
Sequence modifications
A: 1 - 547 (UniProt: E9Q401)
PDBExternal DatabaseDetails
Gln 420Arg 420engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight61549.6
Non-Polymers*Number of molecules1
Total formula weight92.1
All*Total formula weight61641.7
*Water molecules are not included.

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PDB entries from 2024-07-31

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