4L4I
Crystal structure of mouse Ryanodine Receptor isoform 2 (RyR2) 1-547 disease mutant R420Q
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ryanodine receptor 2 | polymer | 547 | 61549.6 | 1 | UniProt (E9Q401) Pfam (PF08709) Pfam (PF02815) Pfam (PF01365) | Mus musculus (mouse) | RYR-2, RyR2, Cardiac muscle ryanodine receptor, Cardiac muscle ryanodine receptor-calcium release channel, Type 2 ryanodine receptor, Cardiac Ca2+ release channel |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A: 1 - 547 (UniProt: E9Q401)
| PDB | External Database | Details |
|---|---|---|
| Gln 420 | Arg 420 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 61549.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 61641.7 |
