4L4I

Crystal structure of mouse Ryanodine Receptor isoform 2 (RyR2) 1-547 disease mutant R420Q

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005219	molecular_function	ryanodine-sensitive calcium-release channel activity
A	0005262	molecular_function	calcium channel activity
A	0006816	biological_process	calcium ion transport
A	0016020	cellular_component	membrane
A	0070588	biological_process	calcium ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 601

Chain	Residue
A	PHE42
A	ARG414
A	ASP458
A	HOH761

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Domain: {"description":"MIR 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00131","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	55
Details	Domain: {"description":"MIR 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00131","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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