4L3Q
Crystal structure of glucokinase-activator complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glucokinase | polymer | 457 | 51163.2 | 1 | UniProt (P35557) Pfam (PF00349) Pfam (PF03727) | Homo sapiens (human) | Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D |
| 2 | B (A) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 3 | C (A) | 6-{3-[(1-methyl-1H-imidazol-2-yl)sulfanyl]phenyl}pyridin-2(1H)-one | non-polymer | 283.3 | 1 | Chemie (926) | |||
| 4 | D (A) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A: 16 - 465 (UniProt: P35557)
| PDB | External Database | Details |
|---|---|---|
| Gly 9 | - | expression tag |
| Pro 10 | - | expression tag |
| Met 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Leu 13 | - | expression tag |
| Thr 14 | - | expression tag |
| Leu 15 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51163.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 463.5 | |
| All* | Total formula weight | 51626.7 |
