4KYO
Alanine-glyoxylate aminotransferase variant K390A in complex with the TPR domain of human Pex5p
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Serine-pyruvate aminotransferase | polymer | 394 | 43132.9 | 2 | UniProt (P21549) Pfam (PF00266) In PDB | Homo sapiens (human) | SPT, Alanine--glyoxylate aminotransferase, AGT |
2 | B, D | Peroxisomal targeting signal 1 receptor | polymer | 328 | 36130.7 | 2 | UniProt (P50542) Pfam (PF13432) Pfam (PF13181) In PDB | Homo sapiens (human) | PTS1 receptor, PTS1R, PTS1-BP, Peroxin-5, Peroxisomal C-terminal targeting signal import receptor, Peroxisome receptor 1 |
3 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | A, C | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 2 | Chemie (BTB) | |||
5 | A, C, B, D | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 12 | Chemie (BME) | |||
6 | water | water | 18.0 | 709 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 392 (UniProt: P21549)
B, D: 315 - 639 (UniProt: P50542)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Ala 390 | Lys 390 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 312 | - | expression tag |
Ala 313 | - | expression tag |
Met 314 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 158527.1 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 1548.2 | |
All* | Total formula weight | 160075.3 |