4KXZ
crystal structure of tgfb2 in complex with GC2008.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, D, E) | Transforming growth factor beta-2 | polymer | 112 | 12732.6 | 4 | UniProt (P61812) Pfam (PF00019) | Homo sapiens (human) | TGF-beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, Polyergin, Latency-associated peptide, LAP |
| 2 | E, F, G, H (H, J, N, Q) | GC1008 Heavy Chain | polymer | 224 | 23907.8 | 4 | Homo sapiens (human) | ||
| 3 | I, J, K, L (I, L, M, P) | GC1008 Light Chain | polymer | 215 | 23425.9 | 4 | Homo sapiens (human) | ||
| 4 | M, N, O, P, Q (A, E, J, Q, M) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 5 | Chemie (MES) | |||
| 5 | R (P) | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL | non-polymer | 398.5 | 1 | Chemie (PE5) | |||
| 6 | AA, BA, CA, DA, S... (I, L, M, P, A...) | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 240265.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1374.7 | |
| All* | Total formula weight | 241640.1 |
