4KU8
Structures of PKGI Reveal a cGMP-Selective Activation Mechanism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | cGMP-dependent Protein Kinase 1 | polymer | 153 | 16945.8 | 3 | UniProt (Q13976) Pfam (PF00027) | Homo sapiens (human) | cGK 1, cGK1, cGMP-dependent protein kinase I, cGKI |
| 2 | D, E, F (A, B) | GLYCINE | non-polymer | 75.1 | 3 | Chemie (GLY) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 344 | Chemie (HOH) |
Sequence modifications
A, B, C: 219 - 369 (UniProt: Q13976)
| PDB | External Database | Details |
|---|---|---|
| Gly 217 | - | expression tag |
| Ser 218 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50837.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 225.2 | |
| All* | Total formula weight | 51062.6 |
