4KFG
The DNA Gyrase B ATP binding domain of Escherichia coli in complex with a small molecule inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA gyrase subunit B | polymer | 215 | 23850.8 | 2 | UniProt (P0AES6) Pfam (PF02518) | Escherichia coli | |
| 2 | C, D, F (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | E, G (A, B) | 6-fluoro-4-[(3aR,6aR)-hexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl]-N-methyl-2-[(2-methylpyrimidin-5-yl)oxy]-9H-pyrimido[4,5-b]indol-8-amine | non-polymer | 434.5 | 2 | Chemie (DOO) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
A, B: 15 - 220 (UniProt: P0AES6)
| PDB | External Database | Details |
|---|---|---|
| Met 14 | - | expression tag |
| Leu 221 | - | expression tag |
| Glu 222 | - | expression tag |
| His 223 | - | expression tag |
| His 224 | - | expression tag |
| His 225 | - | expression tag |
| His 226 | - | expression tag |
| His 227 | - | expression tag |
| His 228 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47701.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1157.1 | |
| All* | Total formula weight | 48858.7 |
