4K94
Crystal structure of KIT D4D5 fragment in complex with anti-Kit antibody Fab19
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | Fab19 heavy chain | polymer | 226 | 24603.2 | 1 | Homo sapiens (human) | ||
| 2 | B (H) | Fab19 light chain | polymer | 220 | 23396.2 | 1 | Homo sapiens (human) | ||
| 3 | C (C) | Mast/stem cell growth factor receptor Kit | polymer | 214 | 24044.9 | 1 | UniProt (P10721) | Homo sapiens (human) | SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| 4 | D (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, F, G (L, H, C) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
C: 308 - 518 (UniProt: P10721)
| PDB | External Database | Details |
|---|---|---|
| Gly 305 | - | expression tag |
| Ala 306 | - | expression tag |
| Met 307 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 72044.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 72265.4 |
