4K8V
Structure of cyclic GMP-AMP Synthase (cGAS)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (C, A, B, D) | Cyclic GMP-AMP synthase | polymer | 362 | 42512.1 | 4 | UniProt (Q8C6L5) Pfam (PF03281) Pfam (PF20266) | Mus musculus (mouse) | cGAMP synthase, cGAS, m-cGAS, Mab-21 domain-containing protein 1 |
| 2 | E, F, G, H (C, A, B, D) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | I, J, K, L (C, A, B, D) | water | water | 18.0 | 1357 | Chemie (HOH) |
Sequence modifications
C, A, B, D: 147 - 507 (UniProt: Q8C6L5)
| PDB | External Database | Details |
|---|---|---|
| Ser 146 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170048.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 170310.1 |
