4K10
Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM and Mg2+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, D, C) | Farnesyl pyrophosphate synthase | polymer | 362 | 41017.2 | 4 | UniProt (Q4QBL1) Pfam (PF00348) | Leishmania major | |
| 2 | E, F, G, L, V... (A, B, C) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 3 | H, I, N, O, S... (A, B, D, C) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 4 | J, P, U, Z (A, B, D, C) | 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM | non-polymer | 302.1 | 4 | Chemie (NI9) | |||
| 5 | K (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | M, R (B, D) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 7 | Q (D) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 8 | AA, BA, CA, DA (A, B, D, C) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 164068.8 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 1960.3 | |
| All* | Total formula weight | 166029.0 |
