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4JPV

Crystal structure of broadly and potently neutralizing antibody 3bnc117 in complex with hiv-1 gp120

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(G)
HIV-1 CLADE A STRAIN 93TH057 GP120 WITH LOOP d AND LOOPD V5 REPLACED FROM HIV STRAIN 3415V1polymer35239182.41UniProt (by SIFTS) (Q0ED31)HUMAN IMMUNODEFICIENCY VIRUS 1
2B
(H)
HEAVY CHAIN OF ANTIBODY 3BNC117polymer22624656.51Homo sapiens (human)
3C
(L)
LIGHT CHAIN OF ANTIBODY 3BNC117polymer20623022.71Homo sapiens (human)
4D, E, F, G, H...
(G, L)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.211Chemie (NAG)
5N
(G)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
6O, P, Q, S
(G, L)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
7T, U, V
(G, H, L)
waterwater18.081Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight86861.6
Non-Polymers*Number of molecules16
Total formula weight2919.9
All*Total formula weight89781.4
*Water molecules are not included.

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PDB entries from 2026-02-04

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