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4JPK

Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain eOD-GT6 in complex with a putative VRC01 germline precursor Fab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
Putative VRC01 germline precursor Fab heavy chainpolymer24826541.61Homo sapiens (human)
2B
(L)
Putative VRC01 germline precursor Fab light chainpolymer21023035.51Homo sapiens (human)
3C
(A)
Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6polymer17218576.91Pfam (PF00516)
UniProt (by SIFTS) (P04578)
Human immunodeficiency virus 1 (HIV-1)
4D, E
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
5F, G, H
(H, L, A)
waterwater18.0173Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight68153.9
Non-Polymers*Number of molecules2
Total formula weight442.4
All*Total formula weight68596.4
*Water molecules are not included.

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PDB entries from 2025-12-17

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