4J23
Low resolution crystal structure of the FGFR2D2D3/FGF1/SR128545 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Fibroblast growth factor receptor 2 | polymer | 223 | 25014.4 | 1 | UniProt (P21802) Pfam (PF07679) Pfam (PF13927) In PDB | Homo sapiens (human) | FGFR-2, K-sam, KGFR, Keratinocyte growth factor receptor |
| 2 | B | Fibroblast growth factor 1 | polymer | 138 | 15615.6 | 1 | UniProt (P05230) Pfam (PF00167) In PDB | Homo sapiens (human) | FGF-1, Acidic fibroblast growth factor, aFGF, Endothelial cell growth factor, ECGF, Heparin-binding growth factor 1, HBGF-1 |
Sequence modifications
A: 147 - 366 (UniProt: P21802)
B: 21 - 155 (UniProt: P05230)
| PDB | External Database | Details |
|---|---|---|
| Met 146 | - | expression tag |
| Leu 367 | - | expression tag |
| Glu 368 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 18 | - | expression tag |
| His 19 | - | expression tag |
| Met 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40630.0 | |
| All* | Total formula weight | 40630.0 |
