4IZK
Crystal structure of yellowtail ascites virus VP4 protease active site mutant (K674A) reveals both an acyl-enzyme complex and an empty active site
Replaces: 4HHCReplaces: 3RBPEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Yellowtail Ascites Virus (YAV) VP4 protease | polymer | 210 | 22269.3 | 1 | UniProt (P89521) Pfam (PF01768) | Yellowtail ascites virus | |
| 2 | B (B) | Yellowtail Ascites Virus (YAV) VP4 protease | polymer | 210 | 22253.3 | 1 | UniProt (P89521) Pfam (PF01768) | Yellowtail ascites virus | |
| 3 | C, E (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | D (B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 320 | Chemie (HOH) |
Sequence modifications
A: 508 - 716 (UniProt: P89521)
B: 508 - 716 (UniProt: P89521)
| PDB | External Database | Details |
|---|---|---|
| Met 507 | - | initiating methionine |
| Ala 674 | Lys 674 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 507 | - | initiating methionine |
| Ala 674 | Lys 674 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44522.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 126.7 | |
| All* | Total formula weight | 44649.4 |
