4ITS
Crystal structure of the catalytic domain of human Pus1 with MES in the active site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | tRNA pseudouridine synthase A, mitochondrial | polymer | 336 | 37950.4 | 1 | UniProt (Q9Y606) Pfam (PF01416) | Homo sapiens (human) | tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I |
| 2 | B (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 3 | C, D, E, F (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | G (A) | water | water | 18.0 | 154 | Chemie (HOH) |
Sequence modifications
A: 79 - 408 (UniProt: Q9Y606)
| PDB | External Database | Details |
|---|---|---|
| Gly 73 | - | expression tag |
| Pro 74 | - | expression tag |
| Gly 75 | - | expression tag |
| Ser 76 | - | expression tag |
| Glu 77 | - | expression tag |
| Phe 78 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37950.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 579.5 | |
| All* | Total formula weight | 38529.8 |
