4ITS
Crystal structure of the catalytic domain of human Pus1 with MES in the active site
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE MES A 501 |
| Chain | Residue |
| A | ARG144 |
| A | HOH602 |
| A | HOH618 |
| A | THR145 |
| A | ASP146 |
| A | VAL149 |
| A | TYR201 |
| A | PHE289 |
| A | MET291 |
| A | LEU333 |
| A | SO4502 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | ALA143 |
| A | ARG144 |
| A | ARG199 |
| A | MES501 |
| A | HOH629 |
| A | HOH753 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| Chain | Residue |
| A | LYS85 |
| A | SER138 |
| A | GLN140 |
| A | ARG223 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 504 |
| Chain | Residue |
| A | LYS83 |
| A | LYS159 |
| A | ARG274 |
| A | GLU275 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 505 |
| Chain | Residue |
| A | HIS292 |
| A | ARG295 |
| A | LYS327 |
| A | HOH744 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"24722331","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ITS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NZ6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
