4IHF

Chasing Acyl Carrier Protein Through a Catalytic Cycle of Lipid A Production

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	polymer	348	36864.2	6	UniProt (P21645) Pfam (PF04613) Pfam (PF00132)	Escherichia coli	UDP-3-O-(3-OHC14)-GlcN N-acyltransferase, Protein FirA, Rifampicin resistance protein
2	G, H, I, J, K... (G, H, I, J, K...)	Acyl carrier protein	polymer	80	8870.7	6	UniProt (G7RM21)	Escherichia coli	ACP
3	M, N (A, D)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	O, P, Q, R, S... (G, H, I, J, K...)	S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] (3R)-3-hydroxytetradecanethioate	non-polymer		584.7	6	Chemie (1F7)
5	AA, BA, CA, DA, EA... (G, H, I, J, K...)	water	water		18.0	920	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 3 - 341 (UniProt: P21645)

PDB	External Database	Details
Met -6	-	expression tag
Gly -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Ala 2	-	expression tag
Ala 239	His 239	conflict

G, H, I, J, K, L: 0 - 77 (UniProt: G7RM21)

PDB	External Database	Details
Ser -2	-	expression tag
His -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	274409.4
Non-Polymers*	Number of molecules	8
	Total formula weight	3579.1
All*	Total formula weight	277988.5

*Water molecules are not included.