4ID1
HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Gag-Pol polyprotein | polymer | 163 | 18152.4 | 1 | UniProt (P12497) Pfam (PF00665) In PDB | Human immunodeficiency virus type 1 (HIV-1) | Pr160Gag-Pol, Matrix protein p17, MA, Capsid protein p24, CA, Spacer peptide p2, Nucleocapsid protein p7, NC, Transframe peptide, TF, p6-pol, p6*, Protease, PR, Retropepsin, Reverse transcriptase/ribonuclease H, Exoribonuclease H, p66 RT, p51 RT, p15, Integrase, IN |
| 2 | A | (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid | non-polymer | 405.5 | 1 | Chemie (LF0) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 78 | Chemie (HOH) |
Sequence modifications
A: 50 - 212 (UniProt: P12497)
| PDB | External Database | Details |
|---|---|---|
| Lys 185 | Phe 1332 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18152.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 693.7 | |
| All* | Total formula weight | 18846.1 |
