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4ID1

HIV-1 Integrase Catalytic Core Domain Complexed with Allosteric Inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0015074biological_processDNA integration
Functional Information from PDB Data
site_idAC1
Number of Residues14
DetailsBINDING SITE FOR RESIDUE LF0 A 301
ChainResidue
ALEU102
AHIS171
ATHR174
AMET178
AHOH427
AHOH458
ATHR124
ATHR125
AALA128
AALA129
ATRP132
AGLN168
AALA169
AGLU170

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE SO4 A 302
ChainResidue
AGLY94
AGLN95
ASER123
ATHR124
ATHR125
ALYS186
AARG187
AHOH431
AHOH440

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 303
ChainResidue
ALYS71
AHIS171
ALEU172
AHOH441
AHOH448

site_idAC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 A 304
ChainResidue
ATHR66
AHIS67

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AASP64
AASP116

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P04585
ChainResidueDetails
AGLU152

227344

PDB entries from 2024-11-13

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