4I2X
Crystal structure of Signal Regulatory Protein gamma (SIRP-gamma) in complex with FabOX117
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | FabOX117 light chain | polymer | 214 | 23660.1 | 2 | Homo sapiens (human) | ||
2 | B, D | FabOX117 heavy chain | polymer | 229 | 24772.8 | 2 | Homo sapiens (human) | ||
3 | E, F | Signal-regulatory protein gamma | polymer | 328 | 36575.3 | 2 | UniProt (Q9P1W8) Pfam (PF07686) Pfam (PF07654) In PDB | Homo sapiens (human) | SIRP-gamma, CD172 antigen-like family member B, Signal-regulatory protein beta-2, SIRP-b2, SIRP-beta-2 |
4 | B | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | D, E | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
7 | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence modifications
E, F: 1 - 319 (UniProt: Q9P1W8)
PDB | External Database | Details |
---|---|---|
Ser 320 | - | expression tag |
Thr 321 | - | expression tag |
Arg 322 | - | expression tag |
His 323 | - | expression tag |
His 324 | - | expression tag |
His 325 | - | expression tag |
His 326 | - | expression tag |
His 327 | - | expression tag |
His 328 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 170016.3 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 578.7 | |
All* | Total formula weight | 170595.0 |