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4I2X

Crystal structure of Signal Regulatory Protein gamma (SIRP-gamma) in complex with FabOX117

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CFabOX117 light chainpolymer21423660.12Homo sapiens (human)
2B, DFabOX117 heavy chainpolymer22924772.82Homo sapiens (human)
3E, FSignal-regulatory protein gammapolymer32836575.32UniProt (Q9P1W8)
Pfam (PF07686)
Pfam (PF07654)
In PDB
Homo sapiens (human)SIRP-gamma, CD172 antigen-like family member B, Signal-regulatory protein beta-2, SIRP-b2, SIRP-beta-2
4BZINC IONnon-polymer65.41Chemie (ZN)
5D, ECHLORIDE IONnon-polymer35.52Chemie (CL)
6E, F2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
7waterwater18.0302Chemie (HOH)
Sequence modifications
E, F: 1 - 319 (UniProt: Q9P1W8)
PDBExternal DatabaseDetails
Ser 320-expression tag
Thr 321-expression tag
Arg 322-expression tag
His 323-expression tag
His 324-expression tag
His 325-expression tag
His 326-expression tag
His 327-expression tag
His 328-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight170016.3
Non-Polymers*Number of molecules5
Total formula weight578.7
All*Total formula weight170595.0
*Water molecules are not included.

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PDB entries from 2024-09-18

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