4HWB

Crystal structure of ectodomain 3 of the IL-13 receptor alpha 1 in complex with a human neutralizing monoclonal antibody fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Interleukin-13 receptor subunit alpha-1	polymer	122	14650.2	1	UniProt (P78552) In PDB	Homo sapiens (human)	IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, Cancer/testis antigen 19, CT19
2	H	Fab heavy chain	polymer	227	24342.4	1		Homo sapiens
3	L	Fab light chain	polymer	212	23132.6	1		Homo sapiens
4	A, H, L	SULFATE ION	non-polymer		96.1	13	Chemie (SO4)
5	A, H	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID	non-polymer		207.3	5	Chemie (NHE)
6		water	water		18.0	77	Chemie (HOH)

Sequence modifications

A: 197 - 310 (UniProt: P78552)

PDB	External Database	Details
His 311	-	expression tag
His 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag
His 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	62125.2
Non-Polymers*	Number of molecules	18
	Total formula weight	2285.3
All*	Total formula weight	64410.5

*Water molecules are not included.