4HT3
The crystal structure of Salmonella typhimurium Tryptophan Synthase at 1.30A complexed with N-(4'-TRIFLUOROMETHOXYBENZENESULFONYL)-2-AMINO-1-ETHYLPHOSPHATE (F9) inhibitor in the alpha site, internal aldimine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tryptophan synthase alpha chain | polymer | 268 | 28698.8 | 1 | UniProt (P00929) Pfam (PF00290) | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 2 | B (B) | Tryptophan synthase beta chain | polymer | 397 | 42918.9 | 1 | UniProt (P0A2K1) Pfam (PF00291) | Salmonella enterica subsp. enterica serovar Typhimurium | |
| 3 | C (A) | 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE | non-polymer | 365.2 | 1 | Chemie (F9F) | |||
| 4 | D, P, Q, R (A, B) | BICINE | non-polymer | 163.2 | 4 | Chemie (BCN) | |||
| 5 | CA, E, EA, GA, HA... (B, A) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 6 | F, V, W (A, B) | CESIUM ION | non-polymer | 132.9 | 3 | Chemie (CS) | |||
| 7 | BA, G, N (B, A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 3 | Chemie (PGE) | |||
| 8 | H (A) | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE | non-polymer | 178.2 | 1 | Chemie (PG5) | |||
| 9 | DA, FA, I, J, K... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 10 | L (B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 11 | AA, Z (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 12 | IA, JA (A, B) | water | water | 18.0 | 765 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71617.7 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 3373.6 | |
| All* | Total formula weight | 74991.3 |
