4HT1
Human TWEAK in complex with the Fab fragment of a neutralizing antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (T) | Tumor necrosis factor ligand superfamily member 12 | polymer | 154 | 17095.7 | 1 | UniProt (O43508) Pfam (PF00229) | Homo sapiens (human) | APO3 ligand, TNF-related weak inducer of apoptosis, TWEAK, Tumor necrosis factor ligand superfamily member 12, membrane form, Tumor necrosis factor ligand superfamily member 12, secreted form |
| 2 | B (H) | chimeric antibody Fab | polymer | 227 | 24084.9 | 1 | Oryctolagus cuniculus | ||
| 3 | C (L) | chimeric antibody Fab | polymer | 218 | 23621.3 | 1 | Oryctolagus cuniculus | ||
| 4 | D, E, F (T, H, L) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
T: 2 - 154 (UniProt: O43508)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 64801.8 | |
| All* | Total formula weight | 64801.8 |
