4HOO
Crystal structure of human JMJD2D/KDM4D apoenzyme
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Lysine-specific demethylase 4D | polymer | 330 | 38021.0 | 2 | UniProt (Q6B0I6) Pfam (PF02375) Pfam (PF02373) In PDB | Homo sapiens (human) | JmjC domain-containing histone demethylation protein 3D, Jumonji domain-containing protein 2D |
| 2 | A, B | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A, B: 12 - 341 (UniProt: Q6B0I6)
| PDB | External Database | Details |
|---|---|---|
| Ala 93 | Lys 93 | engineered mutation |
| Ala 94 | Lys 94 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 76041.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 366.3 | |
| All* | Total formula weight | 76408.2 |
