4HOO
Crystal structure of human JMJD2D/KDM4D apoenzyme
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI A 401 |
| Chain | Residue |
| A | HIS192 |
| A | GLU194 |
| A | HIS280 |
| A | HOH507 |
| A | HOH526 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 402 |
| Chain | Residue |
| A | CYS238 |
| A | HIS244 |
| A | CYS310 |
| A | CYS312 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 403 |
| Chain | Residue |
| A | ASN15 |
| A | ASN17 |
| A | PHE261 |
| A | ASN262 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 404 |
| Chain | Residue |
| A | GLU27 |
| A | HOH528 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI B 401 |
| Chain | Residue |
| B | HIS192 |
| B | GLU194 |
| B | HIS280 |
| B | HOH502 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 402 |
| Chain | Residue |
| B | CYS238 |
| B | HIS244 |
| B | CYS310 |
| B | CYS312 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:B2RXH2 |
| Chain | Residue | Details |
| A | TYR136 | |
| A | ASN202 | |
| A | LYS210 | |
| A | LYS245 | |
| B | TYR136 | |
| B | ASN202 | |
| B | LYS210 | |
| B | LYS245 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000305|PubMed:26741168 |
| Chain | Residue | Details |
| A | HIS192 | |
| A | GLU194 | |
| A | HIS280 | |
| B | HIS192 | |
| B | GLU194 | |
| B | HIS280 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0007744|PDB:5F5A, ECO:0007744|PDB:5F5C |
| Chain | Residue | Details |
| A | CYS238 | |
| A | HIS244 | |
| A | CYS310 | |
| A | CYS312 | |
| B | CYS238 | |
| B | HIS244 | |
| B | CYS310 | |
| B | CYS312 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: PolyADP-ribosyl glutamic acid => ECO:0000269|PubMed:23102699 |
| Chain | Residue | Details |
| A | GLU26 | |
| A | GLU27 | |
| B | GLU26 | |
| B | GLU27 |
