4HKP
Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with CMP-N3-oxide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Uridine 5'-monophosphate synthase | polymer | 312 | 34054.2 | 2 | UniProt (P11172) Pfam (PF00215) In PDB | Homo sapiens (human) | UMP synthase, Orotate phosphoribosyltransferase, OPRT, OPRTase, Orotidine 5'-phosphate decarboxylase, ODC, OMPdecase |
2 | A, B | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
3 | A, B | 5-hydroxycytidine 5'-(dihydrogen phosphate) | non-polymer | 339.2 | 2 | Chemie (TKW) | |||
4 | A | N-hydroxycytidine 5'-(dihydrogen phosphate) | non-polymer | 339.2 | 1 | Chemie (16B) | |||
5 | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 291 (UniProt: P11172)
PDB | External Database | Details |
---|---|---|
Met -20 | - | expression tag |
Gly -19 | - | expression tag |
Ser -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
Gly -8 | - | expression tag |
Leu -7 | - | expression tag |
Val -6 | - | expression tag |
Pro -5 | - | expression tag |
Arg -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 68108.3 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1570.2 | |
All* | Total formula weight | 69678.5 |